Krsna is so attractive that if anyone only once has fully applied his mind in thinking of Krsna and surrendering, then he becomes immediately saved from all miserable condition of this material life. So that is our perfection of life. Somehow or other, we surrender to the lotus feet of Krsna. So here it is stressed, sakrt. Sakrt means "only once." So if so much profit is there simply once thinking of Krsna, then we can imagine, those who are always engaged in thinking of Krsna by chanting the Hare Krsna mantra, what is their position. They are very safe.
Lecture on Srimad-Bhagavatam 6.1.19, Denver, 2 July, 1975