When we are put into great difficulties, it dries up the existence of the senses. No sense enjoyment also can make us happy. Ucchosanam indriyanam. Here happiness means sense gratification. Actually this is not happiness. Real happiness is described in the Bhagavad-gita: atindriyam, sukham atyantikam yat tat atindriyam [BG 6.21]. Real happiness, atyantikam, the supreme happiness, is not enjoyed by the senses. Atindriya, surpassing, transcendental to the senses. That is real happiness. But we have taken happiness as sense enjoyment. So by sense enjoyment, nobody can become happy. Because we are in the material existence. And our senses are false senses. Real senses - spiritual senses.
Lecture on Bhagavad-gita 2.8, London, 8 August, 1973